Vaccine Decision Support System (VADES)
Reliable, personalised, and verifiable vaccine recommendations
OVERVIEW
The Vaccine Decision Support System (VADES) is an expert module developed by SYADEM to automatically generate personalised, justified, verifiable, and directly usable vaccine recommendations for citizens, healthcare professionals, and health authorities.
Originally developed in 2009 and continuously updated, VADES powers digital immunisation pathways. It interprets complex scenarios from a structured vaccination history and a detailed health profile.
WHY VADES?

HOW IT WORKS
Deterministic, rule-based engine
- Written by expert vaccinologists
- Clinically validated test scenarios
- Approved by authorities with full change traceability
- No generative AI — full transparency and auditability
For each vaccine-preventable disease, VADES determines
- Vaccination status (“up to date”, “due”, “delayed”, “contraindicated”…)
- Next dose date
- Recommended vaccine type
- Reference guidelines and sources
- Who may prescribe and administer
- Clinical justification
- Eligibility for reimbursement
INPUT DATA
- Structured vaccination history (NUVA-based)
- Age, sex, pregnancy status
- Medical, occupational, and social risk factors
- Epidemiological/logistical context (shortages, high-risk zones…)
- Objectives: routine, travel, post-exposure…
MENTOR: THE VADES USER INTERFACE
Mentor is available in two versions: one for citizens, one for professionals. Mentor is a standalone web app that harnesses the full power of VADES to deliver a personalised vaccination assessment in four simple steps, with no data storage.
User inputs:
User receives:
TECHNICAL FEATURES
- Deterministic, fully documented system (one verifiable line per rule)
- Tree-structured rule model (branches, leaves, prioritisation)
- Multilingual, multi-country RESTful API with full docs
- Compatible with FHIR, EHRs, national records, and clinical software
ADDED VALUE
- Reduces errors in recommendation implementation
- Continuously updated by subject-matter experts
- Ensures consistency across stakeholders
- Supports ongoing medical education
- Saves time during consultations
INTEGRATION OPTIONS
- Delivered as a SaaS platform
- Custom parameterisation by country/region/institution
- Test case design with national authorities
- Interfaces for citizens, professionals, and decision-makers